The drug Linex is a medicine,Related to probiotics and containing three kinds of beneficial bacteria that act as representatives of the normal microflora of the human intestine. Indications for the appointment of this remedy are violations of the balance of microorganisms, which can be caused by various factors, including treatment with a broad spectrum of antibiotics.
Infringement of intestinal microflora due to admissionDrugs-antibiotics is due to the fact that these drugs are harmful not only to pathogens, but other bacteria. Therefore, those who undergo antibiotic therapy should take care of the recovery of the intestinal microflora. To this end, many experts recommend the use of Linex.
How to take (drink) Linex when taking antibiotics?
The development of intestinal dysbiosis can bePrevent if you start taking the drug Lineks before the planned antibiotic therapy (about a week), and then continue to take it during the treatment and after the treatment course. Due to the fact that Linex contains strains of bacteria that are resistant to most antibiotics, this remedy is effective even when taken together with them.
However, taking Lineks in parallel with the prescribed onesAntibiotic, one should adhere to certain rules. So, adults need to take a given probiotic three times a day for two capsules during a meal. In this case, the antibiotic should be taken at least three hours before taking Linex.
How long to take (drink) Linex with antibiotics?
How much to drink Lineks after antibiotics,Depends on the severity of symptoms of dysbacteriosis and the effectiveness of probiotic therapy. Usually, if Linex was administered concomitantly with antibiotic drugs, it should be drunk for another 7-10 days. During this time, as a rule, the intestinal microflora is restored.
Taylek Drugs Company Ltd Plot 8, Block ‘M’, Abimbola Street, Isolo, P.O.Box, 3344, Mushin, Lagos State.
Lek Pharmaceutical and Chemical Company, Veroskova 57, Ljubjana, Slovenia
Dosage Form, Composition & NAFDAC Registration Number (NRN)
Capsules(NRN): Each hard capsule contains not less than 1.2 x 10 colony forming units of viable lactic acid bacteria species Lactobacillus acidophilus (sp. L. gasseri), Bifidobacterium infantis, Enterococcus faecium.
How to identify the product: White and non-transparent capsule containing white odourless powder.
Pack size: in a brown bottle with 16 hard capsules, Box containing 16 hard capsules in aluminium and hard PVC/PVDC foil blister (1 x 16),
Box containing 16 hard capsules in aluminium blisters (2 x 8)
Linex is a probiotic, which means that it contains lactic acid bacteria which in adequate amount is benefit to health. Linex contains three species of viable lyophilised lactic acid bacteria which regulate the physiological balance of the intestinal microflora, and are resistant to certain antibiotics and chemotherapeutics.
Lactic acid bacteria are normally present in the small and large intestine where they keep the acid-alkaline balance needed for the normal functioning of digestive enzymes, immune system and bowel habit (peristalsis). When the amount of lactic acid bacteria is inadequate the balance of endogenous intestinal bacterial flora is destroyed, resulting in various digestive disorders.
Lactic acid bacteria in Linex are lyophilised (i.e., dried out under low temperature). This allows the storage of the medicine at room temperature without any effect on the form or activity of bacteria.
Linex is used as preventive and as supportive treatment in diarrhea, meteorism and other digestive disorders resulting from microflora imbalance. This can occur at:
- viral and bacterial gastrointestinal infections in infants, children and adults (e.g., rotavirus infection, traveller’s diarrhea)
- treatment with a broad-spectrum antibiotics and chemotherapeutics
- irradiation of abdominal and pelvic organs
Use of probiotic or lactic acid bacteria efficiently lowers the frequency and potency of mild to moderate digestive disorders due to imbalance of intestinal microflora.
Do not take take Linex if you are hypersensitive to any of the active ingredients, or any of the other ingredients of Linex. Before taking Linex, consult your doctor if:
- you have body temperature above 38oC
- you noticed blood or mucus in your stool
- diarrhea lasts more than two days
- you have intense diarrhea accompanied with dehydration and body weight loss
- severe abdominal pain accompanied your diarrhea
- you have other chronic diseases (e.g diabetes, cardio-vascular diseases) or immunodeficient (e.g. HIV infection).
Warning in all age groups: In self treatment of diarrhea, it is the first and the most important action to substitute the loss of liquid and electrolytes.
Warning in infants and children yournger than 6 years: Diarrhea in infants and children younger than six years should be treated only under the doctor supervision.
Pregnancy and breast-feeding:
Self treatment of diarrhea during pregnancy and breast feeding is not recommended. Since there are not enough data or experience in the use of Linex during pregnancy and breast-feeding, we do not recommend its use in these conditions.
Driving and using machines:
No available data on influence of medicine on the ability to drive and use machines.
No clinically significant interaction with other medicinal products has been done so far. In laboraotory studies the natural resistance to certain antibiotics and chemotherapeutics has been determined.
Linex capsules could be taken along with antibiotics and chemotherapeutics, preferably not at the same time. For better efficacy of the medicine, it is recommended to take capsules Linex at least 3 hours after taking antibiotics or chemotherapeutics.
Taking Linex together with food and drink: You should take Linex during meals to avoid harmful effect of stomach juice on lactic acid bacteria. You should not take Linex concomitantly with alcohol or hot beverages.
Side effects after lactic acid bacteria consumption are very rare (less than 1 patient out of 10,000). Reaction or hypersensitivity could occur.
Dosage & Administration
Instruction for proper use:
Linex should be used orally (through the mouth)
You should take Linex at meals to avoid harmful effect of stomach juice on lactic acid bacteria
You should not take Linex concomitantly with alcohol or hot beverages
For a child who is not able to or does not know how to swallow the capsules, open the capsule shell, empty the contents onto a spoon and mix it with some liquid.
The usual dose and duration of treatment:
Infants and children up to 2 years: 1 capsule three times daily
Children aged 2 to 12 years: 1-2 capsules three times daily
Adults and children over 12 years of age: 2 capsules three times daily.
Keep out of the reach of children. Do not store above 25oC.
- Aluminium and PVC/PVDC foil blister: store below 25oC, protected from moisture
- Aluminium foil blisters: store below 25oC, in the original package
- Glass bottle: store below 25oC in tight closed container.
Linex capsules may be used for 4 months after opening the bottle.
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Imbalance of intestinal microflora may be manifested by cramps, painful spasms, constipation and diarrhea. As a rule, these disorders occur after taking antibiotics and due to intestinal infections which are common among young children. To eliminate the unpleasant symptoms of dysbiosis physicians recommend Linex. The advantage of this drug is that it is suitable for all age groups, including newborns.
A goiter can occur even in a newborn baby due to malnutrition of the mother or infectious disease. Artificial feeding, and later breastfeeding, atopic dermatitis or inadequate dietary habits of the mother during pregnancy can also trigger this condition. Indirect signs of this disease are disorders of stool, frequent regurgitation, and weight loss of the baby. To confirm the diagnosis the doctor is likely to prescribe stool cultures, which will help to reveal the deficiency of beneficial bacteria. In the case of confirmation of diagnosis, pediatricians often prescribe Linex. To treat an infant you should sprinkle contents of capsule onto a spoon, dissolve the powder in breast milk or water and give this mixture to the baby. For one course of treatment you will need two packages of the drug, as persistent therapeutic effect is possible only with a ten-day therapy taken three capsules per day.
Preschool children are often exposed to intestinal infection. The reason for that habit is to drag everything into the mouth and cohesive children’s groups in which infection spreads rapidly. In the complex therapy Linex is assigned one capsule three times per day. To violate the integrity of the shell in this case, you should not take the capsule whole, squeezed small amounts of tea or juice.
Students prone to dysbiosis due to irregular and sometimes unhealthy eating habits. Products containing preservatives and dyes adversely affect the gastrointestinal tract. At the onset of symptoms of the disease, the doctor is likely to recommend the admission of Linexand two capsules three times a day.
During antibiotic therapy Linex is used from the first day of treatment. It helps to keep the intestines from the negative effects of antibiotics. Taken by the doctor in the age dosage. Usually, infant and pre-school age are assigned to one capsule, and students.
How to give Linex the child